DETAILED NOTES ON BENZODIAZEPINES AND ALCOHOL

Detailed Notes on benzodiazepines and alcohol

In contrast to other optimistic allosteric modulators that boost ligand binding, benzodiazepine binding acts as a good allosteric modulator by raising the overall conduction of chloride ions through the neuronal mobile membrane when GABA is by now sure to its receptor. This amplified chloride ion influx hyperpolarizes the neuron's membrane prospect

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